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Marketed under the brand name Modalert, modafinil is well known for improving wakefulness and cognitive function, although there isn't much concrete data connecting it to greater neuroplasticity. Nonetheless, modafinil may have advantages due to its effect on neurotransmitters involved in cognitive functions, such as glutamate and dopamine. Modafinil may help neuroplasticity indirectly by enhancing working memory, attention, and executive function. Further encouraging neuroplastic changes, its capacity to lessen fatigue and improve mood may result in a rise in cognitive and physical activity. To definitively ascertain modafinil's effect on neuroplasticity, more investigation is required.